Humic Substences in Drug Development

by R.K. Khar, Rajesh Khanna, S.P. Agarwal

$34.20

$38.00

In stock

Free & Quick Delivery Worldwide

There are a number of natural humic substances which have been identified and used as part of traditional medicine worldwide. The usage has evolved from centuries of knowledge sharing, careful observation and practical experience gained from using these amazing bio-products of nature. Shilajit or Mummiyois one such humic substance that has been used for centuries as part of folk medicine and has been ascribed with miraculous rejuvenating and healing properties. Research over the last century has proven a number of these ancient claims to be true. Recent research by the authors has demonstrated remarkable drug complexing and bioavailability enhancing properties of humic substances derived from Shilajit which can advantageously be used for increasing the solubility, dissolution, permeability and hence bioavailability of problematic drugs of modern system of medicine. A lot of interest has recently been generated amongst the international scientific community in studying the nature and applications of humic substances like Shilajit in modern drug development. The present book tries to collate all this and other remarkable properties of humic substances under one cover. The present book is a single-source reference work to cover the classic as well as modern studies on this traditional herbo-mineral ancient remedy. This book aims to highlight the ancient claims of Shilajit, how these have been validated and reviews information about its occurrence, nature and uses in traditional and modern system of medicine. It also describes the extraction of novel components, fulvic and humic acids from Shilajit and their use as bioavailability enhancers in modern medicine.

Contents:
Humic substances : An introduction, Traditional uses of humic substances in folklore medicine, Shilajit-A humic substance with therapeutic properties, Physicochemical characterization of shilajit, Extraction and characterization of humic substances from shilajit, Surfactant properties of humic substances, Drug complexing properties of humic substances, Solubility-and dissolution-enhancing properties of humic substances, Permeability-enhancing properties of humic substances, Bioavailability-enhancing properties of humic substances, Safety and toxicity studies on humic substances, Humic substances in drug development, References Index

ABOUT THE AUTHOR S.P. Agarwal

Dr. S.P. Agarwal is a Post Graduate in Advanced Electronics Engineering, a Post Graduate in Business Administration and holds a doctoral level degree in International Business. He has a long experience of more than 40 years in R&D, S&T Policy making and administration, technology development & trade, promotion and developing of consulting services, technology incubation, development of small business etc., and has worked in various R&D and commercial organizations. He was Adviser in the Ministry of Science & Technology till 2002. Presently, he is a Professor and Head of the Centre for International Trade in Technology at Indian institute of Foreign Trade, New Delhi. Dr. Agarwal has speical interest in promotion and development of consultancy services, and his taken several initiatives in this direction while he was with the Ministry of Science & Technology or earlier. These included conceptualizing and implementing a Plan scheme for development and promotion of consultancy capabilities in mid eighties, setting up of Consultancy Development Centre at New Delhi, Technical Consultancy Development Programme for Asia and Pacific, supporting consultancy associations and promotional organizations etc., besides research studies and reports. He has been consultant to national and international organizations such as UNDP and ESCAP, and has actively participated in national and international conferences, delegations, trade fairs, etc. in India and abroad. He was invited by ITC and UNIDO for their international meetings for development and cooperation in consultancy services in developing countries, in Geneva and Vienna in mid nineties. He has been on the Boards of Directors of several companies including consultancy companies. He has published more than 100 technical/research papers in India and abroad, including those related to consultancy services. He is perceived to be a champion for the development and promotion of consultancy profession in the country and abroad.