Steroid Analysis in the Pharmaceutical Industry: Harmonal Steroids, Sterols, Vitamins D, Cardiac Glycosides

This unique work describes the analytical chemistry of an important group of pharmaceutical compounds from the viewpoint of the pharmaceutical scientist. It reflects the view of an analytical chemist with 30 years practical and research experience in the pharmaceutical sciences, who has invited a team of specialist experts to collaborate in this exciting and challenging project.  Investigating the spectroscopic, chromtopraphic, immunological and electro-analytical methods used in industrial steroid analysis, the book gives a balance of examples to reflect the special needs of pharmaceutical industrial scientists.  Covering several aspects of the structure elucidation of steroids which occur in pharmaceutics, the authors cover a range of new synthetics products not previously discussed in literate for. The authors present analytical problems associated with the investigation of bulk steroid drugs, dealing with the starting materials of steroid semi-synthesis, with examples of in-process-control merit.  They deal with preformulation studies, discuss assay and stability assay methods, and determine steroids in biological samples from an analytical viewpoint as well as in terms of health control in steroid production.