Textbook of Drug Design and Discovery

Building on the success of the previous edition, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry and medicine. The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final prcesses of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors whilst others examines specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques and combinational approaches are also included. A comprehensive textbook for students from undergraduate to Masters degree level and beyond. Highly illustrated, including color molecular models Includes contributions from some of the world’s leading experts in medicinal chemistry and pharmaceutical research.